I answered the poll with "I have not", and "I hope to someday", thought to be more accurate I'd have answered "It's a part of my summer reading list". I'm at an idle on the MM degree chapter right now, so I can finish another, shorter book which is more specific to my interests (Harmonies of Heaven and Earth: Mysticism in Music from Antiquity to the Avant-Garde). That one should only take a few more days, so I plan on really hitting M&D hard this weekend, after the Reunion on Saturday.
It's not hard reading, really. It is all about understanding the rhythm and syntax that Pike uses. That should take about a chapter to get used to, if you're used to reading college texts. Also, I will agree that these LECTURES (don't forget that that's what they are) are intended to be heard aloud, and reading a bit aloud may help you "get" Pike's style. Although, that method is super slow, and once you've got the flow of the book, you can abandon it.
That said, I started reading it with a PDF. What a horrible reading experience! Dunno about you brothers, but I can't read 800 pages from a computer screen or a cell phone. Anything over a page is just painful. The good news is that a 1963 copy in good condition was only like 10 bucks, with maybe 3 bucks shipping.